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Global infectious diseases are new and re-emerging infectious diseases that were once unknown or thought to be waning, along with recognition that drug resistance, hygiene, economic and environmental factors have promoted both reemergence and increased mortality.

The global infectious diseases includes COVID-19, AIDS, TB, malaria, influenza, and cholera.

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Severe acute respiratory syndrome (SARS) is a viral respiratory disease caused by a SARS-associated coronavirus.  COVID-19 is caused by SARS CoV-2 virus. SARS is an airborne virus and can spread through small droplets of saliva in a similar way to the cold and influenza. It was the first severe and readily transmissible new disease to emerge in the 21st century. SARS can also be spread indirectly via surfaces that have been touched by someone who is infected with the virus.

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Viral infections are any sickness caused from a virus (a small germ that uses your cells to reproduce). Common viral illnesses include colds, the flu, COVID-19, norovirus, HPV, and herpes simplex virus.

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Emerging and Re-Emerging infections are the outbreaks of earlier unidentified infections Identified diseases that are rapidly increasing in occurrence or geographic range in the past 2 decades Persistence of infectious diseases that cannot be controlled. Reemerging diseases are diseases that reappear after they have been on a significant decline.

Emerging infectious diseases include:

  • HIV infections
  • SARS, Lyme disease
  • Escherichia coli O157:H7 (E. coli),
  • Hantavirus,
  • Dengue fever,
  • West Nile Virus
  • Zika virus

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Nosocomial infections also called as healthcare-associated infections (HAI), are infection(s) acquired during the process of receiving health care that was not present during the time of admission.

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Blood Borne Infections are infections caused by the presence of bacteria, virus, fungi can enter the bloodstream. Most common blood borne infection is sepsis. These infections are cured by taking antibiotics.

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Surgical Site Infections are the infections that occurs after surgery in the part of the body where the surgery took place. These infections can be prevented by maintaining good hand hygiene before and during surgery and by using sterilized equipment.

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Neglected and Tropical Infectious Diseases include:

  • Chickenpox (Varicella)
  • Coronaviruses
  • Dengue
  • Diphtheria
  • Ebola
  • Flu (Influenza)
  • Hepatitis
  • Rubella
  • HIV/AIDS
  • Polio
  • Rabies
  • Zika

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Rare Infections are caused by infections mediators rather than genetic or environmental aspects. Some of them are

Chickenpox (Varicella), Coronaviruses, Dengue, Diphtheria, Ebola Virus, Flu (Influenza), Hepatitis, Rubella, HIV/AIDS, Polio, Rabies, Zika Virus

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HIV is a sexually transmitted infection. AIDS (Acquired immunodeficiency Syndrome) is a chronic immune system disease caused by the human immunodeficiency virus (HIV). STD'S are Sexually transmitted diseases (STDs), also known as sexually transmitted infections (STIs), STIs are infections that are spread from person to person through sexual activity, including anal, vaginal, or oral sex. They are caused by bacteria, parasites, and viruses.

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Influenza (flu) is an infection caused by an influenza virus. The flu attacks the lungs, nose and throat which are part of the respiratory system. Symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches and fatigue.

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Pediatric Infections are the childhood infections and disorder, any illness, impairment, or abnormal condition that affects primarily infants and children i.e., those in the age span that begins with the fetus and extends through adolescence.

Common Pediatric Infections include:

  • Chicken Pox (Varicella)
  • Common Colds
  • Conjunctivitis
  • Diarrhea
  • Fifth's Disease (Parvovirus B19)
  • Hand, Foot and Mouth Disease
  • Hepatitis A
  • Hepatitis B

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Gastrointestinal Infection is an infection of the bowel is sometimes called a gastrointestinal infection, or gastroenteritis. Salmonella infection is the most common bacterial infection causing gastroenteritis.

Urinary Tract Infection is an infection in any part of the urinary system, the kidneys, bladder or urethra. They usually occur in the bladder or urethra, but more serious infections involve the kidney. They usually are more common in women.

Symptoms include: pelvic pain, increased urge to urinate, pain with urination and blood in the urine. A kidney infection may cause back pain, nausea, vomiting and fever. The infection can be treated by taking Antibiotics.

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Ebola is a virus that causes severe inflammation and tissue damage throughout the body. It is known as a hemorrhagic fever virus.

Zika Virus transmitted by mosquito bites. In most cases, there are no symptoms. In a few cases, Zika can trigger paralysis (Guillain-Barré Syndrome). In pregnant women, it may cause subsequent birth defects.

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Hepatitis is inflammation of the liver. Inflammation is swelling that happens when tissues of the body are injured or infected. It can damage your liver. This swelling and damage can affect how well your liver functions.

There are different types of hepatitis, with different causes: Viral hepatitis is the most common type. It is caused by one of several viruses -- hepatitis viruses A, B, C, D, and E. In the United States, A, B, and C are the most common. Hepatitis can be prevented by Practicing good hand hygiene — including thoroughly washing hands after using the bathroom, changing diapers, and before preparing or eating food — plays an important role in preventing the spread of hepatitis A. Hepatitis B virus can be easily preventable by a vaccine.

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Respiratory infections are caused by germs (viruses, bacteria or other pathogenic microbes). Germs that can infect the respiratory system are frequently spread through mucus and saliva (also known as "respiratory secretions") when a person coughs, sneezes, talks or laughs.

The most common respiratory infections are: COVID-19, the flu, pneumococcal disease, and colds.

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Neurological infections encompass a large variety of conditions that invade and affect the nervous system. The most common neurological infections are: Encephalitis, an inflammation of the brain, which can be caused by either bacteria or virus. Meningitis, an inflammation of the membranes that cover the brain and spinal cord, which can be caused by either bacteria or virus.

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Communicable diseases are the diseases which passes from one individual to another individual. They are generally caused by some bacteria, viruses or any other pathogens. For example, malaria, AIDS etc. Non-communicable diseases are the diseases which does not spread from one person to another person.

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Orthopedic infections are infections that can affect the bones (osteomyelitis) and joints (septic arthritis). Sometimes these infections occur spontaneously, but more often, they are a complication of surgery, particularly joint replacement surgeries like knee and hip replacement.

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Immunology of infectious disease is a study of how the immune system responds to infectious agents and how infectious agents interact with, modify or evade the immune system.

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  • Infection Control Nursing is assess and evaluation of the isolation procedure done by the unit staff.
  • Detection of incidence of hospital acquired infection and identification of the cause of infection.
    As per hospital rules, ensure that all hospital employees are vaccinated against infectious diseases.

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Infections are caused by germs that enter the body, multiply, and cause harm or illness. The main types of germs that can cause infections are: Bacteria, Viruses and Protozoa.

Symptoms of Infections:

  • Fever (this is sometimes the only sign of an infection).
  • Chills and sweats.
  • Change in cough or a new cough.
  • Sore throat or new mouth sore.
  • Shortness of breath.
  • Nasal congestion.
  • Stiff neck.
  • Burning or pain with urination.

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Infectious Diseases Pathology is a branch and is the primary unit within center for disease control responsible for conducting laboratory studies and investigations of infectious disease of unknown etiologies. Additionally, Infectious Diseases Pathology Branch works to identify new or previously unrecognized pathogens.

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Infectious diseases are diagnosed by detection of a bacterium, virus, fungus, protozoan, in a patient with clinical illness.

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Disinfection is a process that removes dirt, dust, large numbers of microorganisms and organic matter, killing most, but not all viable organisms.

Sterilisation is a process of removing or killing all viable organisms including spores.

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Inflammation is the first response of the immune system to infection or irritation, and may also be elicited by tissue damage due to an uncontrolled/abnormal growth of self-cells. Various immune system cells and their secreted mediators and products are actively involved in this response.

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Infection control procedures used to prevent transmission of diseases that can be acquired by contact with blood, body fluids, non-intact skin (including rashes), and mucous membranes. These measures are to be used when providing care to all individuals, whether or not they appear infectious or symptomatic.

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Standard Infection Control Practice (SICPs)

  • Perform Hand Hygiene.
  • Placement and Infection Assessment.
  • Personal Protective Equipment.
  • Safe Management of Equipment.
  • Safe Disposal of Waste.

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  • Infection control risk assessment involves identifying tasks or activities that carry the risk of introducing or spreading infection.
  • Identifying the people who may be most vulnerable to the spread of infection.
  • Evaluating the risks and implementing precautions and controls.

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Infection control in dental is an ever-growing perturbation. Dental patients are high-risk patients relative to their potential to transmit as well as acquire an infectious disease. An equal concern has been exhibited for cross-contamination and disease transmission from patient to patient.

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Vaccination is a simple, safe, and effective way of protecting you against harmful diseases, before you come into contact with them. It uses your body’s natural defenses to build resistance to specific infections and makes your immune system stronger.

Immunization is a process by which a person becomes protected against a disease through vaccination.

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Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis. Tuberculosis can be spread when an infected person coughs or sneezes.

Tuberculosis can be cured by taking Antibiotics.

Most Common Most common TB drugs:

  • Isoniazid
  • Rifampin
  • Ethambutol
  • Pyrazinamide

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Infection Control measures are of the very important in every ICU. These methods include isolating patients, washing hands, using protective clothing, cleaning and disinfecting equipment, cleaning the environment, and providing education and training.

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Vaccine Research and Development: Recognizing the importance of vaccines as the most cost-effective health intervention for controlling infectious disease burden, the Department of Biotechnology (DBT) has made concerted efforts in the past three decades, towards strengthening vaccine research and development in India.

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Antimicrobial is a drug, chemical or other substance that kills, inactivates or slows the growth of microbes, including bacteria, viruses, fungi and parasites.

Antibacterial is a drug, chemical or other substance that kills bacteria (bactericidal) or stops their growth (bacteriostatic).

Antibiotic is a drug that inhibits the growth or kills bacteria. In recent years, ‘antibiotic’ has become synonymous with ‘antibacterial’.

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Antimicrobial stewardship programs aim to reduce costs, optimize therapeutic outcomes, and reduce antimicrobial resistance. Reductions of antimicrobial resistance are the most elusive because emergence and spread of resistant bacteria involves antimicrobial selective pressure and lapses in infection control techniques.

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Clinical Case Reports are a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. Case reports usually describe an unusual or novel occurrence and as such, remain one of the cornerstones of medical progress and provide many new ideas in medicine.

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Veterinary Infection Control provides guidelines to creating standard operating procedures for effective and efficient infection control in any veterinary practice.

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Infectious plant diseases are mainly caused by pathogenic organisms such as fungi, bacteria, viruses, protozoa, as well as insects and parasitic plants. In agriculture development, infectious plant diseases have become an increasingly significant factor affecting crop yield and economic efficiency.

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Infection prevention and control practices are critical to reduce the transmission of infections from one person to another.

Infection control includes various measures that prevent and contain the spread of infectious disease. These measures include:

 

Emerging infectious diseases in humans has increased within the recent past or threatens to increase in the near future. Over 30 new infectious agents have been detected worldwide in the last three decades; 60 per cent of these are of zoonotic origin. Developing countries such as India suffer disproportionately from the burden of infectious diseases given the confluence of existing environmental, socio-economic, and demographic factors.

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The global market for infectious disease treatments should grow from $72.4 billion in 2021 to $106.3 billion by 2026, at compound annual growth rate (CAGR) of 8.0% for the period of 2021-2026.

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